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Drug Composition information

What is Sildenafil for:

This medication is a phosphodiesterase type 5 (PDE5) inhibitor, prescribed for erectile dysfunction (impotence). Erectile dysfunction is the inability to achieve or maintain an erection long enough to perform sexual intercourse. It relaxes the blood vessels in the penis, allowing more blood to enter to achieve an erection. It can also be used in pulmonary arterial hypertension.

How does Sildenafil work:

Sildenafil helps response to stimulation. It calms lung vessels.

How should Sildenafil be used:

It comes as a tablet to take by mouth and injection to be administered through a vein. To treat pulmonary arterial hypertension it is usually taken three times a day. PO- 50 mg about 1 hour before sexual intercourse. Adjust dose based on response. Max: 100 mgdose and not more than once in 24 hour. Pulmonary Arterial Hypertension- 20 mg 3 times daily. IV- 10 mg (12.5 mL) administered as a bolus injection 3 times daily.

Common side effects of Sildenafil :

Flushing. Wearing layers of clothes or summer clothes and staying in cool places may help. - Low blood pressure. Headache. - Belly pain or heartburn. - Nose stuffiness. Eyesight changes may rarely happen.

What do I do if I miss a dose

Take a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not take 2 doses at the same time or extra doses. Do not change the dose or stop this drug. Talk with the doctor.

What precautions should I take when taking Sildenafil :

If you have an allergy to sildenafil or any other part of this drug. Tell your doctor if you are allergic to any drugs. Make sure to tell about the allergy and what signs you had. This includes telling about rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you use drugs called poppers like amyl nitrite and butyl nitrite. If you have been told not to have sex by your doctor.

When do I need to seek medical help

If you think there was an overdose, call your local poison control center or ER right away. Signs of a very bad reaction to the drug. These include wheezing; chest tightness; fever; itching; bad cough; blue or gray skin color; seizures; or swelling of face, lips, tongue, or throat. Erection that lasts more than 4 hours. Trouble breathing. Chest pain or pressure or a fast heartbeat. Very bad dizziness or passing out. Sudden change or loss of eyesight. Change in hearing. Any rash. Side effect or health problem is not better or you are feeling worse.

Can I take Sildenafil with other medicines:

Sometimes drugs are not safe when you take them with certain other drugs and food. - Taking them together can cause bad side effects. - Be sure to talk to your doctor about all the drugs you take.

Are there any food restrictions

Avoid Alcohol

How do I store Sildenafil :

Store in a cool, dry place away from the reach of children. - Medicines must not be used past the expiry date.

Pregnancy Category

Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Therapeutic Classification

Drugs for Erectile Dysfunction

VIAGRA 50MG TAB - Chennai

Viagra Tablet 50mg

Uses and Benefits

Viagra tablet 50mg is used in men with erectile dysfunction i.e. inability to erect the penis during sexual affairs. It is also used in the treatment of pulmonary arterial hypertension both in both men and women. This tablet also helps to improve exercise capability in adults. However, the uses mentioned here are not exhaustive. There may be other conditions for which this medication may be used upon doctor’s discretion.

Composition

The active ingredient of Viagra Tablet 50mg is Sildenafil 50mg.

Mechanism of Action of Sildenafil

Sildenafil works by increasing blood flow to the penis thus helping it become erect and hard. This drug also relaxes blood vessels in pulmonary hypertension.

Contraindications and Caution

Patients with the following conditions are suggested to seek advice from their health care professional before taking Viagra tablet 50mg:

• Caution:
 
• MIf hepatic impairment
 
• HTN
 
• Moderate to severe BP
 
• Hypovolemia
 
• Aortic stenosis
 
• IHSS
 
• Autonomic dysfunction
 
• MI within 6 months
 
• Stroke within 6 months
 
• Life-threatening arrhythmias within 6 months
 
• Coronary revascularization within 6months
 
• CAD
 
• Diabetes mellitus
 
• Hyperlipidemia
 
• Hereditary degenerative retinal disorders
 
• Penile deformities
 
• Conditions predisposing to priapism
 
• Sickle cell disease
 
• Bleeding risk

Side and Adverse Effects

The following side effects may or may not occur during the usage of Viagra Tablet 50mg. It is generally well tolerated when taken in the prescribed dosage guidelines. More common ones are generally mild and may include:

• Headache
 
• Dyspepsia
 
• Flushing
 
• Epistaxis
 
• Diarrhea (Pulmonary HTN use)
 
• Insomnia
 
• Myalgia
 
• Dyspnea
 
• Erythema
 
• Fever (Pulmonary HTN use)
 
• Rhinitis
 
• UTI (ED use)
 
• Sinusitis
 
• Gastritis
 
• Paresthesia
 
• Visual disturbance
 
• Rash ED use

Rare but more serious adverse effects may include:

• Hypersensitivity reaction
 
• Anaphylaxis
 
• Sudden death
 
• MI (ED use)
 
• Stroke (ED use)
 
• Ventricular arrhythmias (ED use)
 
• Hypotension, severe
 
• Cerebrovascular hemorrhage
 
• Pulmonary hemorrhage
 
• Subarachnoid hemorrhage
 
• Retinal hemorrhage
 
• Non-arteritic ischemic optic neuropathy
 
• Vision loss
 
• Hearing loss
 
• Seizures
 
• Priapism
 
• Anemia (ED use)
 
• Leukopenia (ED use)

How to Use

Do not exceed the dose prescribed by your doctor.
Swallow the tablet immediately after opening the tablet from the strip.
Avoid missing or forgetting a dose. If you do, take it as soon as you remember; but if it is almost time for your next dose, skip it and take it according to your normal schedule. Don’t consume two doses at the same time which is dangerous to your health.
Viagra tablet 50mg may be taken with or without food.
Adults: for Erectile dysfunction take the tablet 1 hour before sexual intercourse.

Overdosage

Avoid taking more than the prescribed dosage. In case of an accidental overdose, promptly seek medical advice. Depending on the dosage, symptoms may vary but you may experience one or more of the following signs or symptoms:

• Hypotension
 
• Syncope
 
• Prolonged ejection

Warnings and Precautions

Take the Viagra Tablet 50mg only on the advice of a medical practitioner. Dosage adjustment or complete avoidance of the medication may be required in the following conditions:

Liver:

Caution advised among people with hepatic problems. If you have any, consult your doctor before the consumption of this medicine.

Pregnancy:

Inform your doctor if you are pregnant or planning to get pregnant because no studies available that this drug may affect an unborn or not. However, consider taking the medication if suggested by a doctor.

Lactation:

This medication may not be safe during breastfeeding. However, inform your doctor and weigh the benefits and risks.

Alcohol:

Alcohol along with this medicine may increase side effects.

Food:

Avoid grapefruit juice because this juice may interact with sildenafil and cause unwanted side effects.

Drug Interactions:

Exercise caution when using with other medicines especially drugs to treat high blood pressure, anti-fungal medicines, and other medicines to treat HIV/AIDS. Do not take medicines which are equivalent to Viagra tablet such as Avanafil, Tadalafil, Vardenafil, etc.

Precautions

• Keep the Viagra Tablet 50mg out of sight and reach of children.
 
• Store below 250C away from heat and moisture.
 
• Do not use the medicine beyond its expiry.
 
• Do not accept torn strip or broken tablet.

FDA Pregnancy Category

Category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.